91¶¶Òõ

COMMUNITY TISSUE CENTER PHASE 1 & 2

NEW BUILD AND EXPANSION

Community Tissue Service's Center for Tissue Innovation and Research (CTIR) located in Kettering, Ohio, is one of the world's premier manufacturing facilities of skin grafts, bone grafts, dental implants and other surgical parts fabricated from tissue donors. 91¶¶ÒõConstruction had previously completed Phase I of CTIR in 2011, a new 94,000 SF facility that included research laboratories, office space and 14 cleanroom production suites. Due to immense growth, CTIR was working three shifts a day and needed additional space for expansion. Given our success on the Phase I project, 91¶¶Òõwas selected as the Construction Manager at Risk for their Phase II expansion, which included a $50 Million, 132,000-square-foot addition of a bio-medical manufacturing facility with 16 ISO Class 5 Cleanrooms, a generator building with three 2.5-megawatt diesel generators, 25-acres of site work, and a new utility plant with connections that fed back into the original 95,000-square-foot manufacturing facility. Additionally, the new facility includes 18 new conference rooms, open collaboration spaces, executive offices, and a 40% larger central sterilization space to sustain the cleanroom workflow.

The 17,000 SF mezzanine houses 26 air handlers providing 500 air changes per hour in the cleanrooms. The cleanroom ceiling system, comprised of 100% HEPA filters, prevents contamination in the manufacturing process. Each cleanroom suite has four stainless steel-clad sliding doors which create the necessary airlock preventing cross-contamination airflow. The new central plant provides redundant chilled water, higher quality steam, reverse osmosis pure water and backup generators which were all fed back into the existing Phase 1 production facility without impacting existing operations. Each system was deliberately designed to prevent a single point of failure to minimize downtime.

CM AT RISK  |  $75.1 MILLION  |  226,000 SF